Contact: Kenna Brigham paffairs@jhsph.edu 410-955-6878 Johns Hopkins University Bloomberg School of Public Health Antioxidant vitamin add-on, extremely vitamins E and C, may safeguard the aging mentality in opposition interrupt associated subsequent to the pathological coppers of Alzheimer's virus, according to a investigation conduct via the Johns Hopkins Bloomberg School of Public Health and other institution.
The researchers whip in antioxidant vitamin supplements may be an of late authorization avoidance strategy all for our aging population by means of they be relatively nontoxic and are spur to grab extensive excitement benefits.
The study, 'Reduced Risk of Alzheimer's Disease delimited by Users of Antioxidant Vitamin Supplements' be published in the January 2004, incentive of the log Archives of Neurology.
Peter P. Zandi, PhD, organize playwright of the study and an partner professor in the School's Department of Mental Health, said, 'These grades are very fast-moving. Our study tender that the even shining up of vitamin E in diet supplement dose, expressly in blend with vitamin C, may get smaller the supposition of evolving Alzheimer's disease.' The researchers examine background from the Cache County Study, which is a sizeable, population-based inquest of the hold and regularity of Alzheimer's disease and other dementias.
Residents who be 65 or elder were assess from 1996-1997 and again from 1998-2000.
Only about partially of the eligible patients agreed to involve yourself in here study, the reviewers noted, and such self-selection reduce the relevance of the study to the standard population.
Approximately 17 percent of the study participants tittle-tattle taking vitamin E or C supplements. These individuals were vitally more scheduled to be womanly, younger, improved conversant and reported better nonspecific health when compared to non-supplement users.
In not compulsory additional to those who take vitamin supplements, another 20 percent of study participants nearly opposite multivitamins, but minus a chubby dosage of vitamin E or C.
The researchers found a trend towards reduced Alzheimer's disease with a combination of vitamin E and C supplements, even after controlling for age, sexual category, lessons and general health.
However, in that be no personage narrowing in the risk of Alzheimer's disease with vitamin E or vitamin C alone or with multivitamins.
Multivitamins routinely include the recommended juncture by day allowance of vitamin E (22 IU or 15 mg) and vitamin C (75-90 mg), while specific supplements contain doses up and about to 1,000 IU of vitamin E and 500-1,000 mg or more of vitamin C.
The researchers run by that the use of vitamins E and C may offer sanctuary against Alzheimer's disease when taken in fellowship in the highly programmed doses bachelor in individual supplements. In addition, there may be quite a few shielding effect with vitamin E when it is public with the pour scorn on doses of vitamin C found in multivitamins.
Dr. Zandi said, 'Further study with randomized prevention trial is needed since plan obdurate conclusions about the protective effects of these antioxidants.
Such trials should balance carrying out tests a regimen of vitamin E and C in combination. If clear, the use of these antioxidant vitamins may offer an exciting strategy for the prevention of Alzheimer's disease.' The study was fund by grant from the National Institutes of Health and National Institute of Mental Health. The Bryan Alzheimer's Disease Center at Duke University completed the APOE genotyping.
James C. Anthony, Ara S. Khachaturian, Stephanie V. Stone, Deborah Gustafson, JoAnn T. Tschanz, Maria C. Norton and John C. S. Breitner co-authored the study.
News emanation from the Johns Hopkins Bloomberg School of Public Health are available at ampills.com/Press_Room.
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