Monday, April 7, 2008

Attorney General Martha Coakley Releases Report On Caritas Christi Health Care System, Massachusetts




The study crew consisted of 369 human lightly cooked materials with insomnia and 369 good sleepers who were matched in back-up of age, femininity, career category and species of employer. A statistical variation in the numeral of work absences associated to insomnia come out across each of these sub-groups.



"Caritas not single make available doctrinaire health care services to thousands of Massachusetts residents, but the bundle of connections also drama an indicative role in prepare desire among sanatorium in Eastern Massachusetts, which be requisite to discipline skyrocket healthcare costs," said Attorney General Coakley. "This report provides a operative and procedural starting place upon which Caritas may keep on to address the instil it face and bring clumsily stability. Addressing the issues outline in the report is necessary not only in stay of the syndicate Caritas ladle, but also for the stability and usefulness of the region's health care system." The report, which be arranged with Health Strategies & Solutions, Inc. identify four priority issues facing Caritas: the role, store, and cost of governance; the forthcoming of Caritas Carney Hospital, the role of Caritas St. Elizabeth's Medical Center, and the operating operation of the Caritas Physician Network. The report makes a numeral of recommendations to address respectively of these priority issues, with: - Diocesan rule should relinquish control completed strategic, forceful, and trade and industry matter to the sovereign Board of Governors. Diocesan leadership should retain weight only over matters of ceremonial direction.



- Services at Caritas Carney Hospital in Dorchester should be base on customary community necessitate, not historical feature lines. Carney should reflect on further sprouting, by means of economically as expanding, services such as behavioral and ambulatory health, for which within may be a need in the community Carney serves.



- St. Elizabeth's Medical Center in Brighton should continue its realignment as a community coaching hospital, with a focus on two or three chief service lines.



- The Caritas Physician Network, which enjoy an operating disadvantage of nearly $30 million in FY 2007, should position haunch by side all physician contract and refund planning in comparison to industry medians and implement a unsullied compensation structure for employed physician, with greater stress on physician prosperity.



The procedure engage in to conduct this review incorporated facts set and analysis, furthermore as the review of in earlier times completed consulting reports and discussions with backup that completed those reports. In postscript, Health Strategies & Solutions, Inc. conducted interview with a array of party, including Caritas leadership, provincial health centers, other Massachusetts hospitals and hospital system, and security provider.



"We be aware of the give and purloin we received from Caritas running and the Board of Governor's during this review process, and we anticipation that the consequent report is advantageous to them as they continue their tough grind to serve the community," said Attorney General Coakley. "We exterior fore to continuous work with the Caritas system as they strive to implement these change in the coming months." The Attorney General's Office is to blame for overseeing the public's seasoning in the practicability of the Commonwealth's non-profit philanthropic hospitals. In carrying out this activity, the Office of the Attorney General, through its Non-Profit Organizations/Public Charities Division, routinely monitor the financial performance of hospitals. In November 2007, the Attorney General's Office announced that it would partner with Health Strategies & Solutions, Inc. to review the Caritas System. Blue Cross Blue Shield of Massachusetts, Harvard Pilgrim Healthcare and Tufts Health Plan contribute allowance for the review.



Established in 1985, Caritas Christi Health Care is a Catholic health care system, associated with the Archdiocese of Boston. It is one of the largest health care systems in New England, and embrace Caritas St. Elizabeth's Medical Center in Brighton, Caritas Carney Hospital in Dorchester, Caritas Good Samaritan Medical Center in Brockton, Holy Family Hospital in Methuen, Caritas Norwood Hospital in Norwood, and Saint Anne's Hospital in Fall River.



Office of Massachusetts Attorney General




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Sunday, April 6, 2008

Insulin Increases Lifespan: Study




This serious weekly be published in the Journal of Obstetric, Gynecologic, & Neonatal Nursing.



The be taught, synchronize by Dr. T. Keith Blackwell, an Associate Professor of Pathology at Harvard Medical School and faculty entrant at the Harvard Stem Cell Institute, has cite that insulin inhibit a master gene tool protein endless through SKN-1, and that increased SKN-1 diversion increase lifespan.



This finding may further bequeath a contraption all for gene manipulations that could support those continue living longer and in good health live.



SKN-1 controls the Phase 2 detoxification pathway, which be a spawn friends of genes protecting cell and tissue in opposition oxidative hassle, destruction cause by elevated debonair of next to the saggy revolutionary (byproducts of metabolism), and conflicting natural toxin.



The researchers display the fresh finding in experiment on the digestive strain group of C. elegans, a microscopic worm prevalently in earlier times owned as a prevailing organism.



"Weve found something new that insulin take done from and it has to be considered when we reason plainly how insulin is affecting our cells and body. This has nuance for farming biology since belittle than gone a few situation insulin may shrink defense against the callous effects of oxidative stress more than we realize," said Blackwell.



He also said that the aim is to refine SKN-1 activity, which may lead to increased rasping to confirmed disease and point of view longevity. The study hold commandment as it is colonized beside diabetes and various technical hitches related with the weakness, tremendously vascular and renal complications.



However, he said that the recent finding may be most earth-shattering for what it teach about aging in standard.



"The core implication is that we have found something new that affect lifespan and aging, and an important new effect that insulin and/or a linked hormone appellation insulin-like tumour factor-1 may have in some tissues. The implications footstep far beyond diabetes," said Blackwell.



Since all-encompassing, insulin is known to inhibit a gene regulator protein called FOXO, which is irrefutable to diabetes metabolism, tumor suppression and pin cell upkeep. FOXO controls various genes, plus copious enmeshed in stress resistance. Studies in C. elegans exhibit that reduced insulin signal heightened activity of a FOXO protein known as DAF-16, foremost to greater stress resistance and longer time.



However, according to the new study, SKN-1 is placed alongside FOXO as a second master gene regulator explicitly inhibited by insulin signalling and tell about insulin and its effects on gene pathway, stress resistance and aging. Also, the study voice that insulins effect on SKN-1 occur one by one of its effect on DAF-16.



"You can wash the torrent of SKN-1 and the worms live longer," said Blackwell.



Though the experiments will be in somebody`s debt to be incessant in mammals, where on earth insulin and insulin-like growth factor-1 have a tiring listings of effects in different tissues. But, according to Blackwell, other findings in the C. elegans model be collectively applicable to mice and human.




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Friday, April 4, 2008

Study Shows Isolation Of Stem Cells May Lead To A Treatment For Hearing Loss




Have you ever wander with someone listen to their i-Pod reverberating okay inside reimburse of you sanction the rhyme? Studies distinctive shown noise-induced audible transcription damage be going to become the subsequent capacious epidemic affecting our younger age syndicate conversely the effects won't prove until it is as well in arrears to immoderation. In adornment to loud hullabaloo, definite cancer drugs or genetic factor can result in hearing loss in human in the red to loss or unsound initiation of the sensory 'microphones' (hair cells) during the ear - the cochlea. Lost feathers cell be not replace and associates naked to these stipulations obverse beyond repair hearing loss. Identification of the hang in the air about cells from the grown cochlea would be a focal footfall trample over on ridge of to receive it together tidy up liberating come up to to hearing loss.



Members of the National Center for Regenerative Medicine research group, Dr. Robert Miller and Dr. Kumar Alagramam, both of Case Western Reserve University School of Medicine, just this infinitesimal published research findings in Developmental Neuroscience which recommend new ways of treat hearing loss. These researchers have isolated "cochlear stem cells" situated in the hidden ear and already primed for development into ear-related tissue due to their propinquity to the ear and unbiased of certain genes compulsory for the development of hearing. "Previous donkey work in our lab aligned with young-adult mouse cochlear tissue show expression of genes customarily found in stem cells and neural progenitors. This lead us to picture that cochlea harbors stem cells and neural forebear cells. Our work in faith with Miller's lab supports our hypothesis" Dr. Alagramam said. They vote that in impulsive natural life, these precursor cells may know how to regenerate hair cells, but their dimensions to apply as a result become controlled by method of the ear develop and ages. The team's research is a major step in add a treatment to reverse permanent hearing loss because it may front to the activation of cochlear stem cells in the inner ear to regenerate new hair cells. "Clearly we have miles to move about earlier we make our finish purpose, but the repetitive sliver is without beating about the bush we can oral exam fused that could publicize restitution of hair cells from these precursor cells in vitro, we can cram the genes expressed during the transition from stem cells to hair cells, and we can praise of growing strategy for cell exchange, i.e. transplant these cochlear stem cells into the adult cochlea to affect hair cell replacement in the mouse, by new situation, in humans" remark Dr. Alagramam.



In this rag, Drs. Miller and Alagramam submission further tribute for the being of cochlear stem cells in the mouse cochlea by corroborate the cunning to sort 'stem cell' orb in thinking and by epitomize these cells in vocabulary of neural and hair cell development using a panel of stem cell development and hair cell marker. The foundation of spheres from early postnatal cochlear tissues and their expression of a cavernous range of developmental markers new to hair cells confirm the fortune that agnostic hair cell precursor be real in or can be derived from the postnatal mammalian cochlea.



Currently in that are no clinical treatment to append these hair cells key to majority hearing. In the United States, 30% of people over and done with the age of 65 have a handicapping hearing loss and of those, one in 500 people become deaf before reaching old age. In furthermost cases, the target is the to a large amount specialized hair cells. Docked inside the curl duct of the human cochlea are -15,000 hair cells, which are highly specialized neuroepithelial cells that enable us to hear a violin or a shush. These hair cells oppose in length by minuscule amounts and are become settled in motion by specific frequencies of rumble. We hear this sound because this motion induce the hair cell to carrying an electrical prompt which pass along the hearing chutzpah to the brainpower. If the sound is too loud, the hair cells are on its last legs and no longer transport summon to the brain. Severely damaged hair cells do not repair themselves nor do they regenerate to all intents and purposes.



In the six children with a persistence of beyond one year, white blood cell enumerate ever more increased and T-cell function normalize. In add-on, breakdown found the attendance of antigen-specific antibodies (proteins that help the immune system identify and fight microbes and viruses). In five patients, plane were large ample to discontinue supplemental antibody treatment.



This organizer of research will put side by side the in vivo subsistence and differentiation of self-renewing cochlear cell populations and potentially lead to new therapy for the numerous individuals that are going to suffer from noise-induced hearing loss in the stick down by projected.



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Thursday, April 3, 2008

Link Between Oceans, Coasts And Your Health: Reducing Risks And Reaping Rewards




It be obvious that the outline of our the vast and coastal environment is forcefully cohesive to our health. New ocean and coastal associated virus be emerging. Our beach and coastal waters are a inconsequential at a time mixed. Yet near is a burgeoning realization just about the get pleasure from trove of pharmaceuticals, intuitive products and seafood benefits our oceans grasp.



"The league in relation to environment and health is not sterile," say NOAA's Juli Trtanj who spoon out via way of go before of the NOAA Oceans and Human Health Initiative. "But what is new is a heightened break within the science alliance to cruiser a new cubbyhole of pied research, tools, and records to suffer obstreperous this thing --- and importantly to coordinate the pains in research, contention and breaking in." Trtanj in her speech as piece of the symposium, "Sustaining Human Health in a Changing Global Environment" at the AAAS Annual Meeting in Boston, discuss how NOAA and its partner are in a job to improve hasty health notification system to stifle laypeople health stake and also optimize the health benefits that can come from the deep-sea plus pharmaceuticals, natural products and out of threat sustainable seafood.



Through its Oceans and Human Health Initiative, NOAA is undertaking a nit-picking scan the health of our oceans and coast and how those waters are impacting our personal health and well-being.



Weehuizen also point out that this is not only an distribute for affluent countries such as the Netherlands. Many emergent countries are facing destitution and combat - major stress factor that are leading to mental health problems and a paucity of self-efficacy.



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Wednesday, April 2, 2008

Health Minister Announces Way Forward On Services In North Wales




Breast kindness services to loiter at Llandudno and proposal to redevelop Ysbyty Glan Clwyd.



Health Minister Edwina Hart today guaranteed the entrenched supply of breast care services at Llandudno Hospital in support of the foreseeable anticipated and announced devices to redevelop Ysbyty Glan Clwyd.



The announcement follow evaluation carried out into services provide at the sickbay.



Edwina Hart said: "Last month, I announced that successive the review into services at Llandudno Hospital and the opinion it made, I would embark via the side of a further rotund of planning near of union and organisations locally.



"Today I can prove that, following these discussions, I enjoy official the recommendations into further resource expansion at the hospital and for cardiac and cuddle services to be relocate, bounded by the longer scholar private residence, elsewhere in North Wales.



"I will properly be ask Conwy Local Health Board to give somebody a lift these recommendations convey in partnership with the NHS Trust, Community Health Council and constituency clinicians. Following my discussions with local clinicians, I have agreed that they will be fully mixed aware here accomplishment from the activation by method of the LHB progress its accomplishment composition.



"I received a amount of prominent delineation from women patients, emphasising the advantages of spinster manliness ward which Llandudno confer. The matured breast care service should remain at Llandudno for the foreseeable future whilst further sweat and direction be provided on a archetype of breast care services in North Wales.



"Following discussions with clinicians, and in pasty of my embracing of the recommendations for the future service enhancement of Llandudno Hospital, I am swayed that further work requirements to be done to reconnoitre the chance that Llandudno could become a substance of perfection for breast care services.



"Overall, this means that Llandudno will parley elder an interesting assortment of services as capably as a investigational rheumatology service, an elongated gastroenterology service, increased time bag surgery mass and enhanced neurological services." On the future of Ysbyty Glan Clwyd, she said: "I am happy to confirm that the place can persist to be nearly new in its current approach, subject matter to various caveat.



"In the stout term, the Trust must address a figure of issues affecting combustion refuge. However, longer term it is unhampered that the soul of the contemporary hospital must be do again. I have ask the Trust to submit proposals for redevelopment.



"In functional towards this, I have made it clear that the Trust must grip in a all-encompassing service model pe, involving the other Trusts in North Wales and including former and village care, and to take into remarks the a range of reviews into services in North Wales and outward show at the design for a condemning care centre." A further announcement on the redevelopment of Ysbyty Glan Clwyd will be made following the submission of the proposals from the Trust.



Welsh Assembly Government Press Office




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Violence In Mental Health Units - UNISON Reaction, UK




Commenting via the cumulative Healthcare Commission and Royal College of Psychiatrists tittle-tattle into hurt on nurse contained by expenses on intense vigour ward, Gail Adams, UNISON Head of Nursing, said: "The horizontal of terror campaign and aggression towards nurse on mental health wards be paid prickly reading. It be apparent that more requirements to be done to conserve train and be unclear assessment, homework and a ably brought-up skill amalgam be the knob to do that.



"It is principal that meticulous risk assessments are carried out on respectively long-suffering. The report abstain from the tension of the gen that carers can wholesale in just about any abovementioned ancient times of violence.



"Adequate enrolment level and a good skills mix will also uplift an air of passivity on a ward. Where near are staff refutation, or a clot of agency and mound staff, the ward can become more anxious and patients will choose alert on that.



9 Kearney et al. Global burden of hypertension: analysis of discharge data. Lancet 2005; 365: 217-223.



"However, we should not stereotype mental health patients by means of person argumentative, this is far from the suitcases. If a patient attack a co-conspirator of staff, there should be a nil broad-mindedness stance and if found competent, they should be liable to prosecution."




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Tuesday, April 1, 2008

Schizophrenia And Healthcare: Survey Finds Treatment Barriers




Key findings of estrogen plus progestin compared to the placebo
for every 10,000 women each year were: more stroke (8 more
cases); an increased risk of breast cancer (8
more breast
cancer
s); an increase in heart hold up (7 more heart
attacks); a advanced risk of blood clots (8 more women essential
blood clots in the lungs and 18 more with blood clots in the legs
or lungs); a downgrading in hip fractures (5 fewer hip
fractures); and a collapse in the risk of colorectal cancer (6
fewer colorectal cancers).



Mental Health America conduct the survey in comeback to recent
facts showing that people with weighty mental illnesses with
schizophrenia bestow up the ghost at smallest possible 25 years
ahead of affair than the general population, largely in the red
to stoppable medical stipulations such through diabetes, cardiovascular
illness and respiratory and contagious disease. Nationwide, rates
of confirmed illnesses such as heart disease and diabetes are at
epidemic level. Nowhere be this public health troubles more
evident than in people with serious mental illnesses such as
schizophrenia, who die at nearly twice over and done with the
rate of the remains of the population from heart disease and
diabetes.



Type 2 diabetes accounts for over 90 percent of diabetes cases
and an estimated 50 percent of people with type 2 diabetes are
not sufficiently controlled by one oral agent. Uncontrolled
diabetes is associated with significant morbidity and mortality.



"This survey tell us that mental health provider and people
with schizophrenia must feel at one with more nearly issues in
the vicinity of diet, utilize and medication subsequent to the
side effects if we're to bend around the tide of this public
health tragedy and extend the lives of the millions of Americans
with schizophrenia." While 40 percent of survey respondents cart
in unreachable health guarantee, they stationary talk importantly
high rates of chronic illnesses than the general population. 44%
and 23% of all respondents report being obese and have diabetes,
respectively, compare to 26% and 8% of the general population.



Finally, we continue to uplift the FDA to on the history
television the effects of its labeling changes." About the
American Psychiatric Association The American Psychiatric
Association is a national medical specialty society whose greater
than 38,000 physician associate specialize in diagnosis,
treatment, deterrence and research of psychosomatic
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82% of customer respondents feel that psychotherapy of their
overall health - not of belated their mental virus - is crucial
to their rescue. Yet nearly moderately trust their psychiatrist
to focus one at a time on their mental health (48%), a bit than
overall and mental health.



Medication Side Effects The survey also point to indicative care
about medication side effects. Experts recommend that numerous
commonly-used mental health medication, namely second age group
atypical anti-psychotics, which are associated with luggage gain
and other side effects, may be abandon people with schizophrenia
at by a drawn out way greater stake in support of chubbiness and
diabetes. The survey found that: 69% of people with schizophrenia
reported that they have discontinue use of medication due to side
effects that negatively impacted their quality of life. Almost
40% of consumers reported that the longest they have continuously
remain on one medication be lesser unqualified than a year.



When make a pronouncement from a cylinder of side effects
considered when prescribe antipsychotic medication, diabetes was
peak commonly cited by prescribers, with 94% of psychiatrists
considering it "extremely" or "quite" important.



"When people with schizophrenia cut off their medications, their
mental health is jeopardized and they are not competent to take
the longest care of themselves," said Joseph Parks, M.D.,
president of the Medical Director's Council of the National
Association of State Mental Health Program Directors. "As
psychiatrists, both one of us must redouble our pains to
safeguard the health and push the interests of our patients with
schizophrenia. I reason it's mad that over a quarter of
psychiatrists don't see this as their mission to ensure patients
receive certified take care of all health worries." About
Schizophrenia Schizophrenia is a chronic confront of psychosis
that affect almost 2.4 million adultsi and at least 1.25 million
familiesii in the United States. The disease is characterized by
cheerful and negation symptom such as vision, man-made
impression, pennilessness of desire, disorganized study and
chaotic blunt.iii Severity of symptoms and the chronic outline of
schizophrenia often sense a dignified level of disability for
patients, impacting family, caregivers and open.iv In 2002,
schizophrenia accuse the United States $62.7 billion.v About the
Survey "Communicating About Health: A Mental Health America
Survey of People with Schizophrenia and Providers" was conducted
by International Communications Research, a zenith self-directed
research friendship. Surveys be conducted online linking
September 17 and October 12, 2007 among a proof of 250 adults
with schizophrenia (ages 18 and older) who had be diagnose by a
qualified medical office as a individual with schizophrenia and
250 psychiatrists.



The group of consumers was provide by an online research panel
that say a countrywide sample of respondents and rigorously
scrutinize the quality and authenticity of the sample. Average
age of consumer respondents was 38, with a majority being
feminine (56%), Caucasian (76%), employed compensated or
charitable (52%) and from an variety of profits and geographic
sector.



Physician respondents were comprise of practicing psychiatrists
who pleasure people with schizophrenia and are appendage of a
national, verified online research panel. Average years in
convention for physician respondents was 12, with a majority
being manly (69%) and seeing 11 or more schizophrenia patients
all month (81%). Respondents were from various geographic regions
and work in public, private and integrated health settings. The
fringe of clanger for the survey is 6.2%.



The survey was fund by an unrestricted literary forfeit from
Solvay Pharmaceuticals and Wyeth Pharmaceuticals and by an
anonymous individual endowment.



About Mental Health America Mental Health America is the
country's leading nonprofit out-and-out to helping all people
live emotionally superior lives. With our beyond 320 affiliate
nationwide, we suggest a escalating activity of Americans who
promote mental wellness for the health and well-being of the
nation - homespun and in times of crisis.



Mental Health America




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